More informations see: http://grants.nih.gov/grants/olaw/references/phspol.htm
This 2015 reprint of the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals (Policy) is available in both printed and electronic formats. The electronic version may be found on the Office of Laboratory Animal Welfare (OLAW) website at OLAW.nih.gov and includes hyperlinks to selected documents referred to in the text.
The 2015 reprint of the PHS Policy reflects the following changes from the 2002 reprint: (1) On January 1, 2012, OLAW adopted the Guide for the Care and Use of Laboratory Animals: Eighth Edition (Guide), an update of the 1996 Seventh Edition, released by the National Academy of Sciences Institute for Laboratory Animal Research (ILAR) in 2011. Institutions with PHS Animal Welfare Assurances implemented the Eighth Edition of the Guide during 2012. (2) On February 26, 2013, the American Veterinary Medical Association (AVMA) Panel on Euthanasia released the AVMA Guidelines for the Euthanasia of Animals: 2013 Edition (Guidelines). PHS Assured institutions implemented the 2013 AVMA Guidelines during the period from March 1, 2013, to September 1, 2013. (3) The OLAW mail address has been removed and electronic and fax contact information has been provided to facilitate efficient communication and conserve resources. (4) Footnotes 2, 7, 9, 11, and 13 have been modified to require PHS Assured institutions to comply with U.S. Department of Agriculture regulations that are applicable to their programs. (5) A change in format, but not content, was made to PHS Policy IV.B.3. (6) Grammatical corrections were made to reflect current writing standards.
This reprint includes the Health Research Extension Act of 1985, Public Law 99-158, “Animals in Research” (November 20, 1985), which provides the statutory mandate for the PHS Policy. Also included in this reprint are the U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research and Training (Principles). The U.S. Principles were promulgated in 1985 by the Interagency Research Animal Committee and adopted by U.S. Government agencies that either develop requirements for or sponsor procedures involving the use of vertebrate animals. The Principles were incorporated into the PHS Policy in 1986 and continue to provide a framework for conducting research in accordance with the Policy.
OLAW, which has responsibility for the general administration and coordination of the Policy, provides specific guidance, instruction, and materials to institutions that must comply with the Policy. For supplemental materials, please contact OLAW at the National Institutes of Health at email@example.com, or visit the OLAW website at OLAW.nih.gov.
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES
NATIONAL INSTITUTES OF HEALTH
OFFICE OF LABORATORY ANIMAL WELFARE